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Angiotensin II/Angiotensin I Ratio as a New Pharmacodynamic Parameter for Population Modelling in Healthy Adults and Children with Heart Failure Treated with Enalapril

<b>Background/Objectives</b>: Since 2023, enalapril orodispersible minitablets have been approved in Europe for paediatric heart failure from birth, but no population pharmacodynamic analyses have yet been conducted in this patient group. The objectives were to investigate the effect of the active m...

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Principais autores: Melina Steichert, Willi Cawello, Bjoern B. Burckhardt, Fabian K. Suessenbach, Stephanie Laeer, on behalf of the LENA Consortium
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2025-10-01
Series:Pharmaceutics
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Acceso en liña:https://www.mdpi.com/1999-4923/17/10/1345
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