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Autologous hematopoietic stem cell transplantation promotes connective tissue remodeling in systemic sclerosis patients

Abstract Background Autologous hematopoietic stem cell transplantation (AHSCT) treats patients with severe and progressive systemic sclerosis (SSc). However, basic mechanisms associated with the therapeutic efficacy of the procedure are not entirely understood. We aimed to evaluate how AHSCT affects...

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Gorde:
Egile Nagusiak: Djúlio C. Zanin-Silva, Maynara Santana-Gonçalves, Marianna Y. Kawashima-Vasconcelos, João R. Lima-Júnior, Juliana B. E. Dias, Daniela A. Moraes, Dimas T. Covas, Kelen C. R. Malmegrim, Leandra Ramalho, Maria Carolina Oliveira
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2022-04-01
Saila:Arthritis Research & Therapy
Gaiak:
Scleroderma and related disorders
Cell transplantation
Skin
Metalloproteinases
Extracellular matrix
Sarrera elektronikoa:https://doi.org/10.1186/s13075-022-02779-w
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