The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal Neurons

Enhanced activity and overexpression of Pannexin 1 (Panx1) channels contribute to neuronal pathologies such as epilepsy and Alzheimer’s disease (AD). The Panx1 channel ablation alters the hippocampus’s glutamatergic neurotransmission, synaptic plasticity, and memory flexibility. Nevertheless, Panx1-...

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Bibliographic Details

Main Authors:	Carolina Flores-Muñoz, Francisca García-Rojas, Miguel A. Pérez, Odra Santander, Elena Mery, Stefany Ordenes, Javiera Illanes-González, Daniela López-Espíndola, Arlek M. González-Jamett, Marco Fuenzalida, Agustín D. Martínez, Álvaro O. Ardiles
Format:	Artigo
Language:	Inglês
Published:	MDPI AG 2022-11-01
Series:	Cells
Subjects:	pannexin 1 actin cytoskeleton neuronal morphology dendritic spines
Online Access:	https://www.mdpi.com/2073-4409/11/22/3646
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