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The number of CD56dim NK cells in the graft has a major impact on risk of disease relapse following allo-HSCT

Abstract: The graft-versus-leukemia (GVL) effect of allogeneic hemopoietic stem cell transplantation (allo-HSCT) is mediated by the donor immune system and acts to decrease the rate of disease relapse. Although studies of posttransplant immune reconstitution have identified correlates of clinical ou...

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Autors principals: Luke Maggs, Francesca Kinsella, Y. L. Tracey Chan, Suzy Eldershaw, Duncan Murray, Jane Nunnick, Joanne Bird, Charles Craddock, Jianmin Zuo, Ram Malladi, Paul Moss
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017-08-01
Col·lecció:Blood Advances
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2473952920302986
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