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YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development

Formation of blood vessel networks by sprouting angiogenesis is critical for tissue growth, homeostasis and regeneration. How endothelial cells arise in adequate numbers and arrange suitably to shape functional vascular networks is poorly understood. Here we show that YAP/TAZ promote stretch-induced...

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Autors principals: Filipa Neto, Alexandra Klaus-Bergmann, Yu Ting Ong, Silvanus Alt, Anne-Clémence Vion, Anna Szymborska, Joana R Carvalho, Irene Hollfinger, Eireen Bartels-Klein, Claudio A Franco, Michael Potente, Holger Gerhardt
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications Ltd 2018-02-01
Col·lecció:eLife
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Accés en línia:https://elifesciences.org/articles/31037
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