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Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent

Abstract The circadian clock regulates cellular and molecular processes in mammals across all tissues including skeletal muscle, one of the largest organs in the human body. Dysregulated circadian rhythms are characteristic of aging and crewed spaceflight, associated with, for example, musculoskelet...

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Hlavní autoři: Deeksha Malhan, Müge Yalçin, Britt Schoenrock, Dieter Blottner, Angela Relógio
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2023-04-01
Edice:npj Microgravity
On-line přístup:https://doi.org/10.1038/s41526-023-00273-4
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