Early-Life Exposure to Environmental Contaminants Perturbs the Sperm Epigenome and Induces Negative Pregnancy Outcomes for Three Generations via the Paternal Lineage

Due to the grasshopper effect, the Arctic food chain in Canada is contaminated with persistent organic pollutants (POPs) of industrial origin, including polychlorinated biphenyls and organochlorine pesticides. Exposure to POPs may be a contributor to the greater incidence of poor fetal growth, place...

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Principais autores:	Clotilde Maurice, Mathieu Dalvai, Romain Lambrot, Astrid Deschênes, Marie-Pier Scott-Boyer, Serge McGraw, Donovan Chan, Nancy Côté, Ayelet Ziv-Gal, Jodi A. Flaws, Arnaud Droit, Jacquetta Trasler, Sarah Kimmins, Janice L. Bailey
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-05-01
Series:	Epigenomes
Assuntos:	persistent organic pollutants (POPs) sperm methylome intergenerational transgenerational epigenetic paternal transmission
Acceso en liña:	https://www.mdpi.com/2075-4655/5/2/10
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