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Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturation

As the resident tissue macrophage of the liver, Kupffer cells (KCs) play an important role in homeostasis and tissue support. However, current in vitro liver models often ignore the contribution of these KCs towards the proper response and function of the tissue. This is especially relevant when we...

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Bibliografische gegevens
Hoofdauteurs: Christopher Zhe Wei Lee, Farah Tasnim, Xiaozhong Huang, Raman Sethi, Yoohyun Song, Tatsuya Kozaki, Sebastiaan De Schepper, Nicholas Ang, Ivy Low, You Yi Hwang, Jinmiao Chen, Hanry Yu, Florent Ginhoux
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications Ltd 2026-06-01
Reeks:eLife
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Online toegang:https://elifesciences.org/articles/108938
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