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Deciphering the microbiological mechanism of Tongxie Yaofang in treating IBS-D: a multimodal mechanistic study in mice integrating network pharmacology, computational simulation, and 16S rRNA sequencing

Irritable bowel syndrome with diarrhea (IBS-D), associated with the traditional Chinese medicine (TCM) pattern of liver hyperactivity with spleen deficiency pattern, lacks effective Western treatments. The modern biological relevance of the “intestine–liver–bile acid” axis aligns with this TCM conce...

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Autori principali: Donglin Yu, Qianghong Tian, Junxi Shen, Leyao Fang, Zhoujin Tan, Ying Cai
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2025-10-01
Serie:Experimental Biology and Medicine
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Accesso online:https://www.ebm-journal.org/articles/10.3389/ebm.2025.10725/full
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