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The effects of prolyl hydroxylase inhibition during and post, hypoxia, oxygen glucose deprivation and oxidative stress, in isolated rat hippocampal slices

The contributions of hypoxia and oxidative stress to the pathophysiology of acute ischemic stroke are well established and can lead to disruptions in synaptic signaling. Hypoxia and oxidative stress lead to the neurotoxic overproduction of reactive oxygen species (ROS) and the stabilization of hypox...

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Principais autores: Niamh Moreton, Martina Puzio, Janet McCormack, John J. O’Connor
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2023-12-01
coleção:Brain Research Bulletin
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0361923023002472
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