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Alternative splicing of HSPA12A pre‐RNA by SRSF11 contributes to metastasis potential of colorectal cancer

Abstract Background Dysregulation of alternative splicing (AS) induced by serine/arginine‐rich proteins has recently been linked to cancer metastasis. Nonetheless, as a member of the serine/arginine‐rich protein family, the involvement of SRSF11 in colorectal cancer (CRC) is unknown. Methods The TCG...

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Principais autores: Yao‐Jie Pan, Fu‐Chun Huo, Meng‐Jie Kang, Bo‐Wen Liu, Meng‐Di Wu, Dong‐Sheng Pei
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2022-11-01
coleção:Clinical and Translational Medicine
Assuntos:
alternative splicing
colorectal cancer
EMT
metastasis
phosphorylation
ubiquitination
Acesso em linha:https://doi.org/10.1002/ctm2.1113
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