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Brain-targeting, acid-responsive antioxidant nanoparticles for stroke treatment and drug delivery

Stroke is the leading cause of death and disability. Currently, there is no effective pharmacological treatment for this disease, which can be partially attributed to the inability to efficiently deliver therapeutics to the brain. Here we report the development of natural compound-derived nanopartic...

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Principais autores: Shenqi Zhang, Bin Peng, Zeming Chen, Jiang Yu, Gang Deng, Youmei Bao, Chao Ma, Fengyi Du, Wendy C. Sheu, W. Taylor Kimberly, J. Marc Simard, Daniel Coman, Qianxue Chen, Fahmeed Hyder, Jiangbing Zhou, Kevin N. Sheth
Formato: Artigo
Idioma:Inglês
Publicado em: KeAi Communications Co., Ltd. 2022-10-01
coleção:Bioactive Materials
Assuntos:
Drug delivery
Acid-triggered release
Antioxidant nanoparticles
NA1
Ischemic stroke
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2452199X22001098
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