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Differences and similarities in the effects of ibrutinib and acalabrutinib on platelet functions

While efficient at treating B-cell malignancies, Bruton tyrosine kinase (BTK) inhibitors are consistently reported to increase the risk of bleeding. Analyzing platelet aggregation response to collagen in platelet-rich plasma allowed us to identify two groups in the healthy population characterized b...

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Autori principali: Jennifer Series, Cédric Garcia, Marie Levade, Julien Viaud, Pierre Sié, Loïc Ysebaert, Bernard Payrastre
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2019-11-01
Serie:Haematologica
Accesso online:https://haematologica.org/article/view/9132
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