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Low NAD+ Levels Are Associated With a Decline of Spermatogenesis in Transgenic ANDY and Aging Mice

Advanced paternal age has increasingly been recognized as a risk factor for male fertility and progeny health. While underlying causes are not well understood, aging is associated with a continuous decline of blood and tissue NAD+ levels, as well as a decline of testicular functions. The important b...

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Hoofdauteurs: Mirella L. Meyer-Ficca, Alexie E. Zwerdling, Corey A. Swanson, Abby G. Tucker, Sierra A. Lopez, Miles K. Wandersee, Gina M. Warner, Katie L. Thompson, Claudia C.S. Chini, Haolin Chen, Eduardo N. Chini, Ralph G. Meyer
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2022-05-01
Reeks:Frontiers in Endocrinology
Onderwerpen:
vitamin B3
niacin
nicotinamide
testis
aging
retinoic acid
Online toegang:https://www.frontiersin.org/articles/10.3389/fendo.2022.896356/full
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