Cellular reprogramming in vivo initiated by SOX4 pioneer factor activity

Abstract Tissue damage elicits cell fate switching through a process called metaplasia, but how the starting cell fate is silenced and the new cell fate is activated has not been investigated in animals. In cell culture, pioneer transcription factors mediate “reprogramming” by opening new chromatin...

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Hlavní autoři:	Takeshi Katsuda, Jonathan H. Sussman, Kenji Ito, Andrew Katznelson, Salina Yuan, Naomi Takenaka, Jinyang Li, Allyson J. Merrell, Hector Cure, Qinglan Li, Reyaz Ur Rasool, Irfan A. Asangani, Kenneth S. Zaret, Ben Z. Stanger
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-02-01
Edice:	Nature Communications
On-line přístup:	https://doi.org/10.1038/s41467-024-45939-z
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