Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

ABSTRACT Epigenetic silencing of tumor suppressor genes is a hallmark of cancer progression. The FXYD (FXYD domain‐containing ion transport regulator) family, classically known for ion transport regulation, has recently been implicated in oncogenesis; however, the role of its founding member, FXYD1,...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Ping Wen, Fanli Qu, Long Wang, Qing Shao, Sisi Li, Yang Qin, Dongping Jiang, Senmiao Zhang, Jiangdong Sui, Guanwen Wang, Ningning Zhang, Xiaohua Zeng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2026-05-01
coleção:	Advanced Science
Assuntos:	breast cancer metastasis DDX5 FXYD1 promoter hypermethylation Wnt/β‐catenin signaling
Acesso em linha:	https://doi.org/10.1002/advs.202521921
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!