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Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice

Summary: Liver injury stimulates hepatocyte replication and hepatic stellate cell (HSC) activation, thereby driving liver regeneration. Aberrant HSC activation induces liver fibrosis. However, mechanisms underlying liver regeneration and fibrosis remain poorly understood. Here, we identify hepatic S...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pingping Wang, Qianqian Kang, Wen-Shu Wu, Liangyou Rui
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2024-03-01
Cyfres:Cell Reports
Pynciau:
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2211124724002031
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