Xanthine Oxidase Inhibitor Allopurinol Prevents Oxidative Stress‐Mediated Atrial Remodeling in Alloxan‐Induced Diabetes Mellitus Rabbits

BackgroundThere are several mechanisms, including inflammation, oxidative stress and abnormal calcium homeostasis, involved in the pathogenesis of atrial fibrillation. In diabetes mellitus (DM), increased oxidative stress may be attributable to higher xanthine oxidase activity. In this study, we exa...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Yajuan Yang, Jianping Zhao, Jiuchun Qiu, Jian Li, Xue Liang, Zhiwei Zhang, Xiaowei Zhang, Huaying Fu, Panagiotis Korantzopoulos, Konstantinos P. Letsas, Gary Tse, Guangping Li, Tong Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2018-05-01
coleção:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Assuntos:	allopurinol atrial fibrillation calcium signaling Diabetes mellitus mitochondria oxidative stress
Acesso em linha:	https://www.ahajournals.org/doi/10.1161/JAHA.118.008807
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!