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Synthesis and Cytotoxic Evaluation of Novel Ester Derivatives of Betulin with AZT, d4T, and 3TC

Novel ester derivatives of betulin with AZT, d4T, and 3TC were synthesized and assessed for antitumor activities against the KB and HepG2 human cancer cell lines in vitro by MTT assay. Some derivatives displayed high anticancer properties, with IC 50 values between 1 and 21 μM on the two cancer cell...

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Autors principals: Dang Thi Tuyet Anh, Le Nhat Thuy Giang, Nguyen Thi Hien, Dinh Thi Cuc, Nguyen Ha Thanh, Nguyen Thanh Tra, Hoang Thi Phuong, Nguyen Van Tuyen, Phan Van Kiem
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publishing 2017-06-01
Col·lecció:Natural Product Communications
Accés en línia:https://doi.org/10.1177/1934578X1701200613
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