Isoxazole–Thiazole Hybrids: Synthesis, Structural Characterisation, Carbonic Anhydrase Inhibition, and Molecular Docking Studies

A new series of isoxazole-fused thiazole–oxazole derivatives (<b>11a–n</b>) was rationally designed and synthesised with the aim of developing potent carbonic anhydrase (CA) I and II inhibitors. The synthesis was achieved in five steps starting from 4-bromoacetophenone, involving key intermediates s...

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Autors principals:	Nurcan Berber, Özge Nur Türkeri, Faika Başoğlu, Kubra Çıkrıkcı, Adem Ergün, Nahit Gencer
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-05-01
Col·lecció:	Molecules
Matèries:	isoquinoline thiazole thiourea carbonic anhydrase enzyme inhibitor
Accés en línia:	https://www.mdpi.com/1420-3049/31/11/1824
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