Saliva-derived DNA is suitable for the detection of clonal haematopoiesis of indeterminate potential

Abstract Clonal haematopoiesis of indeterminate potential (CHIP) has been associated with many adverse health outcomes. However, further research is required to understand the critical genes and pathways relevant to CHIP subtypes, evaluate how CHIP clones evolve with time, and further advance functi...

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Autori principali:	Robert L. O’Reilly, Jared Burke, Philip Harraka, Paul Yeh, Kerryn Howlett, Kiarash Behrouzfar, Amanda Rewse, Helen Tsimiklis, Graham G. Giles, Kristen J. Bubb, Stephen J. Nicholls, Roger L. Milne, Melissa C. Southey
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2024-08-01
Serie:	Scientific Reports
Soggetti:	Clonal haematopoiesis CHIP Somatic mutations Next generation sequencing Saliva Blood
Accesso online:	https://doi.org/10.1038/s41598-024-69398-0
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