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Onvansertib exhibits anti-proliferative and anti-invasive effects in endometrial cancer

Polo-like kinase 1 (Plk1) is widely recognized as an oncogene that promotes cell proliferation by regulating cell division, DNA damage response, and genome stability and has been shown to be overexpressed in many cancers, including endometrial cancer. Targeting Plk1 by onvansertib has been shown to...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Nikita Sinha, Xiaochang Shen, Jennifer Haag, Shuning Chen, Haomeng Zhang, Catherine John, Wenchuan Sun, Michael Emanuele, Chunxiao Zhou, Victoria Bae-Jump
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2025-03-01
Rangatū:Frontiers in Pharmacology
Ngā marau:
Urunga tuihono:https://www.frontiersin.org/articles/10.3389/fphar.2025.1545038/full
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