Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response
Joshi et al. identify two human metabolites, carnosine and kynurenic acid, that rescue a C. elegans model of Alzheimer’s disease by inhibiting the aggregation of the amyloid beta peptide in vivo. They find that these metabolites trigger a cytosolic unfolded protein response through the transcription...
Shranjeno v:
| Principais autores: | , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Portfolio
2021-07-01
|
| Serija: | Communications Biology |
| Online dostop: | https://doi.org/10.1038/s42003-021-02218-7 |
| Oznake: |
Brez oznak, prvi označite!
|