Defects in nerve conduction velocity and different muscle fibre-type specificity contribute to muscle weakness in Ts1Cje Down syndrome mouse model.

BACKGROUND:Down syndrome (DS) is a genetic disorder caused by presence of extra copy of human chromosome 21. It is characterised by several clinical phenotypes. Motor dysfunction due to hypotonia is commonly seen in individuals with DS and its etiology is yet unknown. Ts1Cje, which has a partial tri...

Descripció completa

Dades bibliogràfiques

Autors principals:	Usman Bala, Melody Pui-Yee Leong, Chai Ling Lim, Hayati Kadir Shahar, Fauziah Othman, Mei-I Lai, Zhe-Kang Law, Khairunnisa Ramli, Ohnmar Htwe, King-Hwa Ling, Pike-See Cheah
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2018-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC5967806?pdf=render
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!