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Transvalvular Mechanical Circulatory Support Reverse Remodels the Ischemic Chronic Failing Heart in an Ovine Model

Summary: Sixteen sheep with ischemic chronic heart failure were randomized to either 3 months of Impella 5.5 support (Abiomed) or sham. Myocardial reverse remodeling by Impella support was shown by a significant reduction of end-diastolic volume (Impella 22% reduction, and control 5% increase; P = 0...

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Principais autores: Bart Meyns, MD, PhD, Randi J. Parks, PhD, Erik Verbeken, MD, PhD, Manon van Hecke, MD, Steven Jacobs, MD, PhD, Magdalena Sikole, MD, Charlotte Van Edom, MD, Eveline Bennek Schoepping, PhD, Piet Claus, PhD
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-07-01
coleção:JACC: Basic to Translational Science
Assuntos:
chronic heart failure
mechanical circulatory support
MRI
myocardial infarction
ovine
reverse remodeling
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2452302X25000117
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