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The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1.

We previously performed an RNA interference (RNAi) screen and found that the knockdown of the catalytically inactive phosphatase, MK-STYX [MAPK (mitogen-activated protein kinase) phospho-serine/threonine/tyrosine-binding protein], resulted in potent chemoresistance. Our follow-up studies demonstrate...

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Principais autores: Natalie M Niemi, Juliana L Sacoman, Laura M Westrate, L Alex Gaither, Nathan J Lanning, Katie R Martin, Jeffrey P MacKeigan
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2014-01-01
叢編:PLoS ONE
在線閱讀:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0093896&type=printable
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