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Organoid models established from primary tumors and patient-derived xenograft tumors reflect platinum sensitivity of ovarian cancer patients

Abstract Background Ovarian cancer (OC) remains the deadliest gynecological cancer, primarily due to late-stage diagnosis and high rates of chemotherapy resistance and recurrence. Lack of representative preclinical models complicate the challenges of discovering effective therapies, especially for p...

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Príomhchruthaitheoirí: Parisa Nikeghbal, Dorsa Zamanian, Danielle Burke, Mara P. Steinkamp
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: BMC 2025-09-01
Sraith:BMC Cancer
Ábhair:
Rochtain ar líne:https://doi.org/10.1186/s12885-025-14811-8
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