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Belatacept inhibit human B cell germinal center development in immunodeficient mice

Abstract The humoral response mediated by alloantibodies directed against donor HLA molecules (DSAs) is one of the main causes of graft loss in kidney transplantation. Understanding the pathophysiology leading to humoral kidney rejection as the development of therapeutic tools is therefore a main ob...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chloé Samson, Allan Thiolat, Anissa Moktefi, José L. Cohen, Caroline Pilon, Philippe Grimbert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2023-08-01
Cyfres:Scientific Reports
Mynediad Ar-lein:https://doi.org/10.1038/s41598-023-40700-w
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