Differential effects of heat shock protein 90 and serine 1179 phosphorylation on endothelial nitric oxide synthase activity and on its cofactors.

Endothelial nitric oxide synthase (eNOS) is responsible for maintaining systemic blood pressure, vascular remodeling and angiogenesis. Previous studies showed that bovine eNOS serine 1179 (Serine 1177 for human eNOS) phosphorylation enhanced NO synthesis. Meanwhile, heat shock protein 90 (Hsp90) pla...

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Detalhes bibliográficos

Principais autores:	Yuanzhuo Chen, Bojie Jiang, Yugang Zhuang, Hu Peng, Weiguo Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2017-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC5487052?pdf=render
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