Androgen Receptor, Although Not a Specific Marker For, Is a Novel Target to Suppress Glioma Stem Cells as a Therapeutic Strategy for Glioblastoma

Targeting androgen receptor (AR) has been shown to be promising in treating glioblastoma (GBM) in cell culture and flank implant models but the mechanisms remain unclear. AR antagonists including enzalutamide are available for treating prostate cancer patients in clinic and can pass the blood–brain...

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Autors principals:	Nan Zhao, Fei Wang, Shaheen Ahmed, Kan Liu, Chi Zhang, Sahara J. Cathcart, Dominick J. DiMaio, Michael Punsoni, Bingjie Guan, Ping Zhou, Shuo Wang, Surinder K. Batra, Tatiana Bronich, Tom K. Hei, Chi Lin
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2021-05-01
Col·lecció:	Frontiers in Oncology
Matèries:	androgen receptor glioblastoma cancer stem cells AR antagonist enzalutamide
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fonc.2021.616625/full
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