Nucleotide sequence as key determinant driving insertions at influenza A virus hemagglutinin cleavage sites

Abstract Highly pathogenic avian influenza viruses (HPAIVs) emerge from H5 and H7 low pathogenic avian influenza viruses (LPAIVs), most frequently upon insertions of nucleotides coding for basic amino acids at the cleavage site (CS) of the hemagglutinin (HA). The exact molecular mechanism(s) underly...

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Autors principals:	Monique I. Spronken, Mathis Funk, Alexander P. Gultyaev, Anja C. M. de Bruin, Ron A. M. Fouchier, Mathilde Richard
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-05-01
Col·lecció:	npj Viruses
Accés en línia:	https://doi.org/10.1038/s44298-024-00029-1
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