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Respiratory dysfunction in two rodent models of chronic epilepsy and acute seizures and its link with the brainstem serotonin system

Abstract Patients with drug-resistant epilepsy can experience respiratory alterations, notably during seizures. The mechanisms underlying long-term alterations in respiratory function remain unclear. As the brainstem 5-HT system is a prominent modulator of respiratory function, this study aimed at d...

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Huvudupphov: Hayet Kouchi, Michaël Ogier, Gabriel Dieuset, Anne Morales, Béatrice Georges, Jean-Louis Rouanet, Benoît Martin, Philippe Ryvlin, Sylvain Rheims, Laurent Bezin
Materialtyp: Artigo
Språk:Inglês
Utgiven: Nature Portfolio 2022-06-01
Serie:Scientific Reports
Länkar:https://doi.org/10.1038/s41598-022-14153-6
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