Chemotherapy-induced intestinal epithelial damage directly promotes galectin-9-driven modulation of T cell behavior

Summary: The intestine is vulnerable to chemotherapy-induced damage due to the high rate of intestinal epithelial cell (IEC) proliferation. We have developed a human intestinal organoid-based 3D model system to study the direct effect of chemotherapy-induced IEC damage on T cell behavior. Exposure o...

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Autors principals:	Suze A. Jansen, Alessandro Cutilli, Coco de Koning, Marliek van Hoesel, Cynthia L. Frederiks, Leire Saiz Sierra, Stefan Nierkens, Michal Mokry, Edward E.S. Nieuwenhuis, Alan M. Hanash, Enric Mocholi, Paul J. Coffer, Caroline A. Lindemans
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2024-06-01
Col·lecció:	iScience
Matèries:	Molecular biology Immunology Stem cells research Cancer
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2589004224012975
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