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The Role of Hippo Signaling Pathway and ILK in the Pathophysiology of Human Hypertrophic Scars and Keloids: An Immunohistochemical Investigation

Background: Keloids and hypertrophic scars are characterized by abnormal fibroblast activation and proliferation. While their molecular pathogenesis remains unclear, myofibroblasts have been associated with their development. Hippo pathway effectors YAP/TAZ promote cell proliferation and matrix stif...

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Principais autores: Ilias G. Petrou, Sofia Nikou, Srinivas Madduri, Martha Nifora, Vasiliki Bravou, Daniel F. Kalbermatten
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-10-01
Serier:Cells
Fag:
keloids
Hippo pathway
ILK
hypertrophic scars
wound healing
scars
Online adgang:https://www.mdpi.com/2073-4409/11/21/3426
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