Angiotensin II Directly Increases Endothelial Calcium and Nitric Oxide in Kidney and Brain Microvessels In Vivo With Reduced Efficacy in Hypertension

Background The vasoconstrictor effects of angiotensin II via type 1 angiotensin II receptors in vascular smooth muscle cells are well established, but the direct effects of angiotensin II on vascular endothelial cells (VECs) in vivo and the mechanisms how VECs may mitigate angiotensin II–mediated va...

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Principais autores:	Alejandra Becerra Calderon, Urvi Nikhil Shroff, Sachin Deepak, Audrey Izuhara, Greta Trogen, Alicia A. McDonough, Susan B. Gurley, Jonathan W. Nelson, János Peti‐Peterdi, Georgina Gyarmati
Format:	Artigo
Jezik:	Inglês
Izdano:	Wiley 2024-05-01
Serija:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Teme:	DAF‐FM GCaMP6 sex specificity hypertension losartan PD123319
Online dostop:	https://www.ahajournals.org/doi/10.1161/JAHA.123.033998
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