Pigs lacking the SRCR5 domain of CD163 protein demonstrate heritable resistance to the PRRS virus and no changes in animal performance from birth to maturity

Porcine reproductive and respiratory syndrome (PRRS) is one of the world’s most persistent viral pig diseases, with a significant economic impact on the pig industry. PRRS affects pigs of all ages, causing late-term abortions and stillbirths in sows, respiratory disease in piglets, and increased sus...

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Hlavní autoři:	Clint Nesbitt, Lucina Galina Pantoja, Benjamin Beaton, Ching-Yi Chen, Matt Culbertson, Perry Harms, Justin Holl, Andrzej Sosnicki, Srinu Reddy, Marisa Rotolo, Elena Rice
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-03-01
Edice:	Frontiers in Genome Editing
Témata:	pigs porcine PRRS gene editing CRISPR disease resistance
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fgeed.2024.1322012/full
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