Selectively hampered activation of lymph node-resident dendritic cells precedes profound T cell suppression and metastatic spread in the breast cancer sentinel lymph node

Abstract Background Immune regulated pathways influence both breast cancer (BrC) development and response to (neo)adjuvant chemotherapy. The sentinel lymph node (SLN), as the first metastatic site, is also the first site where BrC-induced suppression of immune effector subsets occurs. Since intricat...

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Egile Nagusiak:	Kim M. van Pul, Ronald J.C.L.M. Vuylsteke, Rieneke van de Ven, Elisabeth A. te Velde, Emiel J. Th. Rutgers, Petrousjka M. van den Tol, Hein B.A.C. Stockmann, Tanja D. de Gruijl
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMJ Publishing Group 2019-05-01
Saila:	Journal for ImmunoTherapy of Cancer
Gaiak:	Dendritic cell Sentinel lymph node Immune suppression Breast cancer
Sarrera elektronikoa:	http://link.springer.com/article/10.1186/s40425-019-0605-1
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