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Machine-Learning Guided Discovery of Bioactive Inhibitors of PD1-PDL1 Interaction

The selective activation of the innate immune system through blockade of immune checkpoint PD1-PDL1 interaction has proven effective against a variety of cancers. In contrast to six antibody therapies approved and several under clinical investigation, the development of small-molecule PD1-PDL1 inhib...

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Xehetasun bibliografikoak
Egile Nagusiak: Sachin P. Patil, Elena Fattakhova, Jeremy Hofer, Michael Oravic, Autumn Bender, Jason Brearey, Daniel Parker, Madison Radnoff, Zackary Smith
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2022-05-01
Saila:Pharmaceuticals
Gaiak:
Sarrera elektronikoa:https://www.mdpi.com/1424-8247/15/5/613
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