Environmental enrichment and physical exercise prevent stress-induced social avoidance and blood-brain barrier alterations via Fgf2

Abstract Chronic stress promotes blood-brain barrier (BBB) integrity loss leading to passage of inflammatory mediators in mood-regulating brain areas and establishment of depressive behaviors. Conversely, neurovascular adaptations favoring stress resilience and preventive strategies to promote them...

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Autores principales:	Sam E. J. Paton, José L. Solano, Alice Cadoret, Adeline Collignon, Luisa Bandeira Binder, Béatrice Daigle, Laura Menegatti Bevilacqua, Émanuelle Richer, François Coulombe-Rozon, Laurence Dion-Albert, Katarzyna A. Dudek, Signature Consortium, Manon Lebel, Caroline Ménard
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2026-01-01
Colección:	Nature Communications
Acceso en línea:	https://doi.org/10.1038/s41467-025-68058-9
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