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Thyroid hormone receptor beta signaling is a targetable driver of prostate cancer growth

Abstract Thyroid hormone (TH) signaling plays a major role in the development, energy homeostasis, and metabolism of most tissues. Recent studies have identified THs as drivers of prostate cancer (PCa) development and progression. We reported that the T3-scavenger protein µ-crystallin (CRYM) regulat...

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Furkejuvvon:
Váldodahkkit: Aleksandra Fesiuk, Daniel Pölöske, Elvin D. de Araujo, Geordon A. Frere, Timothy B. Wright, Gary Tin, Yasir S. Raouf, Olasunkanmi O. Olaoye, Ji Sung Park, Nicolas Blavet, Boris Tichý, Michaela Schlederer, Sandra Högler, Michael Wolf, Cécile Philippe, Osman Aksoy, Adam Varady, Alejandro Medaglia Mata, Maxim Varenicja, Boglárka Szabó, Theresa Weiss, Gabriel Wasinger, Torben Redmer, Heidi A. Neubauer, Martin Susani, Clemens P. Spielvogel, Jing Ning, Maik Dahlhoff, Martin Schepelmann, Richard Kennedy, Richard Moriggl, Geoffrey Brown, Jenny Persson, Christopher Gerner, Vojtech Bystry, Oldamur Hollóczki, David M. Heery, Patrick T. Gunning, Olaf Merkel, Brigitte Hantusch#, Lukas Kenner
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2025-10-01
Ráidu:Molecular Cancer
Fáttát:
Thyroid hormone receptor β
Prostate cancer
NH-3
Androgen receptor
Murine PCa model
Liŋkkat:https://doi.org/10.1186/s12943-025-02451-2
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