Role of bioavailability and protein binding of four anionic perfluoroalkyl substances in cell-based bioassays for quantitative in vitro to in vivo extrapolations

Perfluoroalkyl substances (PFAS) are persistent and pose a risk to human health. High throughput screening (HTS) cell-based bioassays may inform risk assessment of PFAS provided that quantitative in vitro to in vivo extrapolation (QIVIVE) can be developed. The QIVIVE ratio is the ratio of nominal (C...

Descripció completa

Dades bibliogràfiques

Autors principals:	Weiping Qin, Luise Henneberger, Julia Huchthausen, Maria König, Beate I. Escher
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2023-03-01
Col·lecció:	Environment International
Matèries:	Per- and polyfluoroalkyl substances (PFAS) Solid phase microextraction (SPME) Freely dissolved concentration (Cfree) Peroxisome proliferator-activated receptor gamma (PPARγ) Quantitative in vitro to in vivo extrapolation (QIVIVE)
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0160412023001307
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!