Immunotoxicity of Four Per- and Polyfluoroalkyl Substances Following 28-Day Oral Repeat Dosing in Rats Assessed by the Anti-Sheep Red Blood Cell IgM Response

Some PFASs are immunotoxic in rodent models and associated with diminished vaccine response in exposed humans. This study assessed the immunotoxicity of four PFASs via the T cell-dependent IgM antibody response (TDAR) to sheep red blood cells (SRBCs) in adult male rats following 28-day oral repeat d...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Michael F. Hughes, Michael J. DeVito, Grace Patlewicz, Russell S. Thomas, Linda D. Adams, Jeffrey L. Ambroso, Xi Yang, Bindu G. Upadhyay, Stefanie C. M. Burleson, Elaina M. Kenyon
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2025-06-01
Schriftenreihe:	Toxics
Schlagworte:	perfluoroalkyl substance polyfluoroalkyl substance immunotoxicity repeat dose IgM oral
Online-Zugang:	https://www.mdpi.com/2305-6304/13/6/490
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