Linalyl acetate alleviates inflammatory pain via OLFR482 activation in the mouse anterior cingulate cortex

IntroductionChronic pain severely impairs quality of life and causes heavy socioeconomic burdens worldwide. Linalyl acetate (LA), a major volatile terpenoid ester from essential oils, possesses potential analgesic effects.MethodsA CFA-induced chronic inflammatory pain mouse model was established. Be...

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Principais autores:	Ban Feng, Wei Guo, Shu Zhao, Han Wang, Xinshang Wang, Kun Zhang, Dake Song, Peng Gao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-07-01
coleção:	Frontiers in Pharmacology
Assuntos:	anterior cingulate cortex chronic inflammatory pain linalyl acetate neuronal excitability olfactory receptors
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1867848/full
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