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Gut microbiota and metabolites in acute lung injury: mechanisms and therapeutic perspectives

Abstract Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS), represent a clinical syndrome with high mortality, characterized by excessive pulmonary inflammation and oxidative stress. Despite advancements in conventional supportive care, mortality rates for ALI/A...

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Main Authors: Shuyuan Yi, Xiaoli Zhuang, Lan Luo, Lin Fu, Ziyuan Dong, Kan Wang, Yu Jiang, Xiaofang Yang, Feilong Hei
Format: Artigo
Language:Inglês
Published: BMC 2026-01-01
Series:Respiratory Research
Subjects:
Acute lung injury/acute respiratory distress syndrome
Gut microbiota
Gut-lung axis
Metabolites
Online Access:https://doi.org/10.1186/s12931-026-03525-5
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