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Protocol for measuring NLRC4 inflammasome activation and pyroptosis in murine bone-marrow-derived macrophages

Summary: NLR family CARD domain containing protein 4 (NLRC4) inflammasome activation and the associated pyroptosis are critical for protection against infection by bacterial pathogens. This protocol presents a detailed procedure to activate and measure NLRC4 inflammasome activation and pyroptosis up...

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Principais autores: Xingchen Dong, Lin-Feng Chen
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021-12-01
Serier:STAR Protocols
Fag:
Cell Biology
Immunology
Microbiology
Microscopy
Molecular Biology
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666166721006006
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