Learning and actioning general principles of cancer cell drug sensitivity

Abstract High-throughput screening of drug sensitivity of cancer cell lines (CCLs) holds the potential to unlock anti-tumor therapies. In this study, we leverage such datasets to predict drug response using cell line transcriptomics, focusing on models’ interpretability and deployment on patients’ d...

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Үндсэн зохиолчид:	Francesco Carli, Pierluigi Di Chiaro, Mariangela Morelli, Chakit Arora, Luisa Bisceglia, Natalia De Oliveira Rosa, Alice Cortesi, Sara Franceschi, Francesca Lessi, Anna Luisa Di Stefano, Orazio Santo Santonocito, Francesco Pasqualetti, Paolo Aretini, Pasquale Miglionico, Giuseppe R. Diaferia, Fosca Giannotti, Pietro Liò, Miquel Duran-Frigola, Chiara Maria Mazzanti, Gioacchino Natoli, Francesco Raimondi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2025-02-01
Цуврал:	Nature Communications
Онлайн хандалт:	https://doi.org/10.1038/s41467-025-56827-5
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!