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Silibinin-Loaded Proniosomal Gel for Cutaneous Application: Pharmaco-Technical Characterization and In Vitro–In Ovo Biocompatibility

The skin serves as the first line of defense, being highly prone to external damage. Silibinin (SIL) exerts skin-protective properties, but its topical use requires a suitable delivery system. Despite the growing interest in proniosomal platforms loaded with natural products, their application for t...

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Principais autores: Andreea Smeu, Ioana Olariu, Iasmina Marcovici, Diana Haj-Ali, Lavinia Vlaia, Vicențiu Vlaia, Alina Tănase, Raluca Mioara Cosoroabă, Vlad Socoliuc, Cristina Adriana Dehelean
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-06-01
Serier:Gels
Fag:
silibinin
proniosomal gel
pharmaco-technical evaluation
safety profile
keratinocytes
spheroids
Online adgang:https://www.mdpi.com/2310-2861/12/6/504
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