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IL-6 contributes to metastatic switch via the differentiation of monocytic-dendritic progenitors into prometastatic immune cells

Background Metastasis is the major cause of death in patients with cancer. Myeloid skewing of hematopoietic cells is a prominent promoter of metastasis. However, the reservoir of these cells in the bone marrow (BM) compartment and their differentiation pattern from hematopoietic stem and progenitor...

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Hlavní autoři: Michael Timaner, Ziv Raviv, Shai Shen-Orr, Yuval Shaked, Tongwu Zhang, Ksenia Magidey-Klein, Tim J Cooper, Ksenya Kveler, Rachelly Normand, Brian P. James, Roi Gazit, Ze'ev A. Ronai
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2021-06-01
Edice:Journal for ImmunoTherapy of Cancer
On-line přístup:https://jitc.bmj.com/content/9/6/e002856.full
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