A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse

Abstract Background Chronic neuroinflammation, aggressive amyloid beta (Aβ) deposition, neuronal cell loss, and cognitive impairment are pathological presentations of Alzheimer’s disease (AD). Therefore, resolution of neuroinflammation and inhibition of Aβ-driven pathology have been suggested to be...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Min Sung Gee, Seung Hwan Son, Seung Ho Jeon, Jimin Do, Namkwon Kim, Yeon-Joo Ju, Soo Jin Lee, Eun Kyoung Chung, Kyung-Soo Inn, Nam-Jung Kim, Jong Kil Lee
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2020-04-01
سلاسل:	Alzheimer’s Research & Therapy
الموضوعات:	Alzheimer’s disease Amyloid-β P38 mitogen-activated protein kinase Kinase inhibitor Microglia
الوصول للمادة أونلاين:	http://link.springer.com/article/10.1186/s13195-020-00617-2
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!