Progranulin Is a Useful Biomarker to Predict Mortality in ICU Patients with Low Burden of Organ Dysfunction

<b>Background/Objectives</b>: Early prognostication in critically ill patients with low burden of organ dysfunction (BOD) remains challenging. Progranulin (PGRN), a hypoxia inducible and anti-inflammatory protein, may offer prognostic value. We investigated whether PGRN levels predict mortality in I...

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Autori principali:	Jochen Johannes Schoettler, Lutz Pridzun, Bertram Flehmig, Holger A. Lindner, Verena Schneider-Lindner, Joerg Krebs, Franz-Simon Centner, Manfred Thiel
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2026-03-01
Serie:	Biomedicines
Soggetti:	progranulin critical illness mortality prediction organ dysfunction
Accesso online:	https://www.mdpi.com/2227-9059/14/4/744
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